Best Flea and Tick Treatment in NYC (2025)

Seresto Large Dog Vet-Recommended Flea & Tick Treatment & Prevention Collar for Dogs Over 18 lbs. | 8 Months Protection

★★★★☆4.2

(4,676 verified reviews)

Why We Ranked It #1

Claiming the #1 spot, this flea and tick treatment stands out with its 4.2/5 rating from 4,676 reviews. NYC customers consistently praise its reliability and performance for city living.

Key Features

✓To view this video download
✓Vet-recommended, premium flea & tick protection for dogs & puppies without the price tag
✓Long-lasting flea and tick collar kills & repels fleas for 8 continuous months
✓Seresto is the #1 veterinarian recommended flea & tick collar*
✓Starts working within 24 hours to kill & repel fleas by contact so pests don’t have to bite your dog to die

Great for NYCFast Prime Shipping4.2+ Star RatingTop Seller

Seresto Small Dog Vet-Recommended Flea & Tick Treatment & Prevention Collar for Dogs Under 18 lbs. | 8 Months Protection

★★★★☆4.4

(5,556 verified reviews)

Why We Ranked It #2

Securing the #2 position, this option impressed us with its solid 4.4/5 rating across 5,556 reviews. It's an excellent alternative to our top pick with slightly different strengths.

Key Features

✓To view this video download
✓Vet-recommended, premium flea and tick protection for dogs and puppies without the price tag
✓Long-lasting flea and tick collar kills and repels fleas for 8 continuous months
✓Seresto is veterinarian recommended flea and tick collar
✓Starts working within 24 hours to kill and repel fleas by contact so pests don’t have to bite your dog to die

Great for NYCFast Prime Shipping4.4+ Star RatingTop Seller

Premium Pick

$44.99

Seresto Cat Vet-Recommended Flea & Tick Treatment & Prevention Collar for Cats | 8 Months Protection

★★★★☆4.3

(1,957 verified reviews)

Why We Ranked It #3

Taking third place, this premium option is worth the investment for those wanting top-tier performance. Its 4.3/5 rating from 1,957 buyers reflects exceptional build quality.

Key Features

✓To view this video download
✓Vet-recommended, premium flea & tick protection for cats & kittens without the price tag
✓Long-lasting flea and tick collar kills & repels fleas for 8 continuous months
✓Seresto is the #1 veterinarian recommended flea & tick collar*
✓Starts working within 24 hours to kill & repel fleas and ticks by contact so pests don’t have to bite your cat to die

Great for NYCFast Prime Shipping4.3+ Star RatingTop Seller

Best Value

$44.99

PetArmor Plus Flea and Tick Prevention for Dogs, Large Dog Flea and Tick Treatment, 6 Doses, Waterproof Topical, Fast Acting (45-88 lbs)

★★★★☆4.4

(2,487 verified reviews)

Why We Ranked It #4

Our #4 pick offers the sweet spot between price and performance. At its price point with a 4.4/5 rating from 2,487 reviews, it's hard to beat for budget-minded NYC shoppers.

Key Features

✓To view this video download
✓Effective, Waterproof Flea Treatment for Dogs: PetArmor Plus is a waterproof flea and tick treatment for dogs that kills fleas, eggs, larvae, ticks, and chewing lice up to 30 days after application
✓Fast Acting Long-Lasting Dog Flea & Tick Control: One application of PetArmor Plus lasts up to 30 days providing nose to tail protection. A 6-dose package lasts six months
✓Easy-to-use, Long-Lasting: PetArmor Plus tick and flea prevention for dogs comes with six (6) waterproof topical applications that provide your pet flea protection and control for six (6) months

Great for NYCFast Prime Shipping4.4+ Star RatingTop Seller

Best Overall

$44.99

FRONTLINE Plus Flea and Tick Treatment for Large Dogs Up to 45 to 88 lbs. 3 Treatments

★★★★☆4.4

(3,188 verified reviews)

Why We Ranked It #5

Rounding out our recommendations, this flea and tick treatment earned its spot with solid performance and 3,188 positive reviews averaging 4.4/5.

Key Features

✓To view this video download
✓Treat all dogs or cats in your household monthly to effectively control fleas and ticks and prevent the establishment of new flea infestations
✓Subscribe & save today to make it easier to keep your dogs or cats protected year-round and make sure you never run out of FRONTLINE Plus
✓Subscribe & save today to make it easier to keep your dogs or cats protected year-round and make sure you never run out of FRONTLINE Plus

Great for NYCFast Prime Shipping4.4+ Star RatingTop Seller